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Updated: Dec 11, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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Many faces of the GPCR-arrestin interaction

Kiae Kim1, Ka Young Chung2

  • 1School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, 16419, Republic of Korea.

Archives of Pharmacal Research
|August 18, 2020
PubMed
Summary

G protein-coupled receptors (GPCRs) interact with arrestins, influencing signaling. Understanding the structural basis of these interactions is key to developing biased GPCR drugs with fewer side effects.

Keywords:
ArrestinGPCRStructure

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