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MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening
Published on: October 26, 2017
What radiologists should know about microRNA (miRNA) serum biomarkers for germ cell tumors
Matthew A Morgan1, Joanie M Garratt2, David J Vaughn3
1Department of Radiology, Hospital of the University of Pennsylvania, University of Pennsylvania of the Health System, 1 Silverstein, 3400 Spruce St, Philadelphia, PA, 19103, USA. Matthew.Morgan@pennmedicine.upenn.edu.
Abstract:
MicroRNAs expressed by germ cell tumors represent a novel approach to detection of metastatic disease during staging, surveillance, and recurrence post-therapy. It has particular promise in settings of equivocal imaging, such as clinical stage I GCT, tumor marker negative stage IIA, or after chemotherapy. These miRNAs have the potential to change typical serum marker evaluation and imaging surveillance schedules.
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