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Published on: July 18, 2014
[Acute amiodarone pulmonary toxicity with low impregnation dose: case report]
Julio O Cabrera-Rego1, José D Luzurriaga Navas2, Alberto A Yanes Quintana3
1Unidad de Cuidados Coronarios Intensivos, Hospital Manuel Fajardo, La Habana, Cuba. Adress: Zapata y D, Vedado, Plaza de La Revolución, La Habana, Cuba, Código postal: 10400. Email: jocabrera@infomed.sld.cu. ORCID: 0000-0001-9372-6203.
Abstract:
Amiodarone, considered a potent antiarrhythmic, is known to cause pulmonary toxicity. Chronic interstitial pneumonitis is the most common presentation. However, acute pulmonary toxicity is rare and has a higher case fatality rate. We present a 61-year-old patient with persistent atrial fibrillation who, after a one-month treatment with oral amiodarone at a low dose impregnation of 400 mg/day, develops acute pulmonary toxicity, with radiographic and tomographic resolution after antiarrhythmic suspension and steroid treatment.
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