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Renal dysfunction following high-dose carboplatin treatment.
P O Mulder1, D T Sleijfer, E G de Vries
1Department of Intensive care Medicine, University Hospital, Groningen, The Netherlands.
Journal of Cancer Research and Clinical Oncology
|January 1, 1988
Summary
High-dose carboplatin can cause renal failure in patients with pre-existing kidney issues and prior cisplatin treatment. Careful monitoring of kidney function is crucial during and after this intensive chemotherapy regimen.
Area of Science:
- Nephrology
- Oncology
- Pharmacology
Background:
- A patient with compromised renal function due to nephrectomy and prior cisplatin chemotherapy received high-dose carboplatin.
- The carboplatin was administered as part of a conditioning regimen before autologous bone marrow transplantation.