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A case study of pyoderma gangrenosum.

V L Young1, B Fernando, M Tabas

  • 1Division of Plastic Surgery, Washington University School of Medicine, St. Louis, MO 63110.

The Journal of Hand Surgery
|March 1, 1988
PubMed
Summary
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Pyoderma gangrenosum, a rare skin condition, can manifest on the hand, particularly in patients with myelofibrosis. This case highlights a rare instance of hand pyoderma gangrenosum post-splenectomy.

Area of Science:

  • Dermatology
  • Hematology
  • Internal Medicine

Background:

  • Pyoderma gangrenosum is a rare neutrophilic dermatosis characterized by painful skin pustules or bullae that rapidly ulcerate.
  • It is frequently associated with inflammatory bowel disease and other systemic conditions like myelofibrosis.
  • Pyoderma gangrenosum of the hand is exceptionally rare, with limited documented cases.

Observation:

  • This article details a patient diagnosed with myelofibrosis.
  • The patient developed pyoderma gangrenosum on her hand.
  • The onset of symptoms occurred after the patient underwent a splenectomy.

Findings:

  • This case presents a rare occurrence of pyoderma gangrenosum affecting the hand.
  • The patient had a history of myelofibrosis, a condition sometimes linked to pyoderma gangrenosum.

Related Experiment Videos

  • The development of pyoderma gangrenosum followed a splenectomy procedure.

    • Implications:

    • This case expands the understanding of pyoderma gangrenosum presentation, particularly its rare manifestation on the hand.
    • It underscores the importance of considering pyoderma gangrenosum in patients with myelofibrosis, especially after surgical interventions like splenectomy.
    • Further research may elucidate the specific mechanisms linking myelofibrosis, splenectomy, and hand pyoderma gangrenosum.