Related Experiment Video
Updated: Dec 11, 2025

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Pediatric contact allergens in the neonatal intensive care unit
Jodie Raffi1, Nicole Kittler1, Kathryn Schwarzenberger2
1Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Objective:
The degree of neonatal exposure to potentially sensitizing agents on neonatal intensive care units (NICUs) and the process by which personal care products are selected for use in the NICU are poorly documented.
Study Design:
We evaluated personal care products used in three NICUs for potentially sensitizing agents. We interviewed NICU staff to analyze how products are selected and approved for use.
Results:
Twenty-four personal care products were evaluated. 75% contained one or more potential contact allergen, with fragrances being most common. Staff preference, brand loyalty, cost, and small product size were often considered when approving NICU products.
Conclusions:
The prevalence of potentially sensitizing agents in the products indicates a need for improvement in the evaluation and acquisition process of over-the-counter products used for neonatal skin care. The involvement of dermatology in this process may be beneficial.
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