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Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Published on: August 14, 2019
A Systematic Review of ASL Perfusion MRI in Mild TBI
Yang Wang1, Hannah M Bartels2, Lindsay D Nelson2
1Department of Radiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. yangwang@mcw.edu.
Mild traumatic brain injury (mTBI) likely causes changes in cerebral blood flow (CBF) detectable by arterial spin labeling (ASL). Further research is needed to confirm these findings and understand individual differences in mTBI recovery.
Area of Science:
- Neuroscience
- Radiology
- Public Health
Background:
- Mild traumatic brain injury (mTBI) is a significant public health issue.
- Cerebrovascular alterations are critical in mTBI recovery and long-term effects.
- Arterial spin labeling (ASL) offers noninvasive cerebral blood flow (CBF) quantification.
Conclusions:
- mTBI is likely associated with ASL-derived CBF anomalies.
- High-quality, larger-scale prospective studies are required.
- Further research should explore individual factors influencing post-injury CBF changes.
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