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Updated: Dec 11, 2025

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction
Published on: January 19, 2016
Synthesis of Thermoplastic Poly(2-methoxyethyl acrylate)-Based Polyurethane by RAFT and Condensation Polymerization
Shunsuke Tazawa1, Tomoki Maeda1,2, Masamitsu Nakayama1,3
1Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223-8522, Japan.
Abstract:
Thermoplastic solid poly(2-methoxyethyl acrylate) (PMEA)-based polyurethane (PU) is synthesized through the reversible addition-fragmentation chain transfer (RAFT) polymerization and the condensation polymerization, using hydroxyl-terminated RAFT reagents and diisocyanate, respectively. Neat PMEA is a promising antithrombogenic liquid used in the medical fields. The thermoplastic property of the solid PMEA-based PU due to hydrogen bonding is confirmed by the dynamic mechanical analysis (DMA) at temperature below 72 °C. The antithrombogenic property of PMEA-based PU is also analyzed by the platelet adhesion test. The number of platelets on PMEA-based PU is 17 cells per unit area, which is smaller than that on the fluorinated diamond-like carbon (F-DLC), a well-known highly antithrombogenic material. It is concluded that a newly synthesized PMEA-based PU exhibits thermoplastic characteristics with excellent antithrombogenicity.
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