Preventing the progression of human renal disease: have rational therapeutic principles emerged?

Delayed branching of endothelial capillary-like cords in glycated collagen I is mediated by early induction of PAI-1.

American journal of physiology. Renal physiology·2001

Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia.

Kidney international. Supplement·2000

Hypoxia-induced changes in extracellular matrix metabolism in renal cells.

Experimental nephrology·1999

The concept of glomerular self-defense.

Kidney international·1999

Inference of the existence of high blood pressure as a cause of renal disease in the mid-19th century: observations on vascular structures in the kidney.

American journal of nephrology·1999

British contributions to renal physiology: Of dynasties and diuresis.

American journal of nephrology·1999

Technology-Supported Solutions to Improve Guideline-Informed Care for Kidney Disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Kidney international·2026

An individual patient meta-analysis assessed the associations between change in albuminuria and acute changes in the glomerular filtration rate in randomized controlled trials of chronic kidney disease progression.

Kidney international·2026

Podocyte GIT1 and GIT2 ArfGAPs cooperatively sustain the ARHGEF7-Cdc42 axis and glomerular permselectivity.

Kidney international·2026

Data from the French Daily-Luma cohort suggest predictors of a lumasiran response.

Kidney international·2026

Prospective 96-week study to evaluate efficacy and safety of tacrolimus and glucocorticoid against mycophenolate and glucocorticoid as continuous induction-maintenance treatment for Class III/IV without or with Class V lupus nephritis.

Kidney international·2026

Tubular Rev-erbα deficiency aggravates kidney fibrosis via transcription factor NFIL3-driven lipid accumulation.

Kidney international·2026

Integrating a Tumor Size-Overall Survival Model Into a Spatial Quantitative Systems Pharmacology Framework for Antibody-Drug Conjugates in Non-Small Cell Lung Cancer.

CPT: pharmacometrics & systems pharmacology·2026

The Future of all-Comers Trials in the Era of Precision Oncology.

Clinical pharmacology and therapeutics·2026

Tumor Treating Fields Enhance Temozolomide-Associated Growth Suppression in Glioblastoma Cells and Patient-Derived Organoids Through Cell-Cycle Blockade, Apoptosis, and SMAD-Associated Signaling.

CNS neuroscience & therapeutics·2026

MyoD and Myogenin regulatory cascade is targeted by tumor signals to repress myogenesis in cancer cachexia.

The Biochemical journal·2026

Beyond the cerebrospinal fluid: Preclinical and clinical evidence on central nervous system penetration and functional activity of oral rapamycin (sirolimus).

Journal of Alzheimer's disease : JAD·2026

Conferone: Sources, Anticancer Mechanisms, and Potential in Overcoming Chemoresistance - A Comprehensive Review.

Current pharmaceutical design·2026

Related Experiment Videos

Preventing the progression of human renal disease: have rational therapeutic principles emerged?

Related Concept Videos

Delayed branching of endothelial capillary-like cords in glycated collagen I is mediated by early induction of PAI-1.

Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia.

Hypoxia-induced changes in extracellular matrix metabolism in renal cells.

The concept of glomerular self-defense.

Inference of the existence of high blood pressure as a cause of renal disease in the mid-19th century: observations on vascular structures in the kidney.

British contributions to renal physiology: Of dynasties and diuresis.

Technology-Supported Solutions to Improve Guideline-Informed Care for Kidney Disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

An individual patient meta-analysis assessed the associations between change in albuminuria and acute changes in the glomerular filtration rate in randomized controlled trials of chronic kidney disease progression.

Podocyte GIT1 and GIT2 ArfGAPs cooperatively sustain the ARHGEF7-Cdc42 axis and glomerular permselectivity.

Data from the French Daily-Luma cohort suggest predictors of a lumasiran response.

Prospective 96-week study to evaluate efficacy and safety of tacrolimus and glucocorticoid against mycophenolate and glucocorticoid as continuous induction-maintenance treatment for Class III/IV without or with Class V lupus nephritis.

Tubular Rev-erbα deficiency aggravates kidney fibrosis via transcription factor NFIL3-driven lipid accumulation.

Integrating a Tumor Size-Overall Survival Model Into a Spatial Quantitative Systems Pharmacology Framework for Antibody-Drug Conjugates in Non-Small Cell Lung Cancer.

The Future of all-Comers Trials in the Era of Precision Oncology.

Tumor Treating Fields Enhance Temozolomide-Associated Growth Suppression in Glioblastoma Cells and Patient-Derived Organoids Through Cell-Cycle Blockade, Apoptosis, and SMAD-Associated Signaling.

MyoD and Myogenin regulatory cascade is targeted by tumor signals to repress myogenesis in cancer cachexia.

Beyond the cerebrospinal fluid: Preclinical and clinical evidence on central nervous system penetration and functional activity of oral rapamycin (sirolimus).

Conferone: Sources, Anticancer Mechanisms, and Potential in Overcoming Chemoresistance - A Comprehensive Review.

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Preventing the progression of human renal disease: have rational therapeutic principles emerged?

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