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Updated: Aug 16, 2026

Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis
Published on: October 28, 2022
Retinal Pigment Epithelial Detachment in Age-Related Macular Degeneration
Michael Karampelas1, Panagiotis Malamos2, Petros Petrou3
1Ophthalmology Department, Hippokration General Hospital, Athens, Greece. mikekarampelas@hotmail.com.
Abstract:
Retinal pigment epithelial detachment is defined as a separation of the retinal pigment epithelium from the inner collagenous layer of Bruch's membrane. It is a common manifestation in both dry and wet types of age-related macular degeneration. This review aims to provide a comprehensive guide to the pathophysiology, clinical and imaging characteristics, natural course and treatment of the various types of pigment epithelial detachments in order to assist in diagnosis and management of this important feature of age-related macular degeneration.
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