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Anthropometric, Biochemical, and Food Consumption Parameters are Associated with Venous Leg Ulcer Area and Duration
Paulla G Melo1, João F Mota, Cynthia A B Nunes
1At the Federal University of Goias, Goiania, Goias, Brazil, Paulla G. Melo, PhD, is a nutritionist, Health Sciences Postgraduate Program; João F. Mota, PhD, is Full Professor, Faculty of Nutrition; Cynthia A. B. Nunes, PhD, is Full Professor, Faculty of Nursing; Kelle V. A. Amaral, MSc, is a nurse, Nursing Postgraduate Program; Alexandre S. G. Coelho, PhD, is Full Professor, Agronomy College; and Maria M. Bachion, PhD, is Full Professor, Faculty of Nursing. Acknowledgments: The authors thank the NUTADIES team responsible for interprofessional care of study participants. This research was funded by the Foundation for Research Support of the State of Goias (Fundação de Amparo à Pesquisa do Estado de Goiás-FAPEG; PPSUS 201410267000321) and the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico-CNPq; 487093/2013-5). The authors have disclosed no other financial relationships related to this article. Submitted September 19, 2019; accepted in revised form October 22, 2019.
Objective:
To describe the dietary habits and anthropometric and biochemical parameters of patients with active venous leg ulcers and to verify the association of these variables with wound duration and area.
Design, Setting, And Participants:
A cross-sectional study conducted with 33 participants diagnosed with venous leg ulcers in outpatient care.
Main Outcome Measures:
Socioeconomic data, anthropometric parameters, biochemical parameters, food consumption, and wound characteristics were analyzed by an interprofessional team.
Main Results:
Participants were an average of 58 ± 13 years, 57.6% women, 84.8% overweight, and had a median wound duration of 10 months (range, 1-192 months) and an average wound area of 5 cm (range, 0.22-61.1 cm). Diets were typically hypocaloric and hypoproteic, with a low amount of vitamin A and magnesium. Wound duration was negatively associated with polyunsaturated fat intake (P = .032), whereas wound area was significantly associated with lipid intake (P = .002) and C-reactive protein (P = .040).
Conclusions:
Patients with active venous leg ulcers were overweight (leading to systemic inflammation) and had low consumption of calories, protein, and micronutrients that could support cicatrization. Wound area was associated with a high-fat diet, whereas wound duration was negatively associated with polyunsaturated fat intake.
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