Interatrial block and cognitive impairment in the BAYES prospective registry

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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

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Manuel Martínez-Sellés1, M Esther Martínez-Larrú2, Martin Ibarrola3

  • 1Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, Universidad Europea, Universidad Complutense, Madrid, Spain; CIBERCV, Madrid, Spain.

International Journal of Cardiology
|August 19, 2020
PubMed

Insights

Interatrial block (IAB), a heart condition, is linked to cognitive impairment (CI) in older adults with heart disease. Both partial and advanced IAB predict future cognitive decline.

Area of Science:

  • Cardiology
  • Neurology
  • Geriatrics

Background:

  • A potential link between interatrial block (IAB) and dementia has been proposed.
  • This study aimed to investigate the association between IAB and cognitive impairment (CI).

Purpose of the Study:

  • To assess the relationship between interatrial block (IAB) and cognitive impairment (CI) in elderly patients with structural heart disease.
  • To determine if IAB is an independent predictor of cognitive decline.

Main Methods:

  • Prospective study of 552 patients aged 70+ with structural heart disease in sinus rhythm.
  • Cognitive function assessed using the Pfeiffer test at baseline and every 6 months.
  • Median follow-up of 22 months.

Main Results:

  • 30 patients (5.4%) had baseline CI. Higher prevalence of advanced IAB in patients with CI (46.7% vs 23.4%).
  • Advanced IAB independently associated with baseline CI (OR 4.9).
  • Both partial and advanced IAB independently associated with CI at follow-up (HR 1.98 and 2.04, respectively).

Conclusions:

  • Advanced IAB is associated with baseline cognitive impairment in elderly patients with structural heart disease in sinus rhythm.
  • Partial and advanced IAB are associated with the development of cognitive impairment during follow-up.
Abstract

Keywords:
Atrial fibrillationBayés syndromeCognitive impairmentDementiaInteratrial block

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