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Self-reported medication adherence tools in cardiovascular disease: protocol for a systematic review of measurement
Henok G Tegegn1, Edouard Tursan D'Espaignet, Stuart Wark
11School of Rural Medicine, University of New England, Armidale, Australia 2Department of Clinical Pharmacy, School of Pharmacy, University of Gondar, Gondar, Ethiopia 3School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.
Insights
This review identifies reliable self-reported tools to measure medication adherence in adults with cardiovascular disease. Accurate measurement aids in managing chronic conditions and improving patient health outcomes.
Area of Science:
- Cardiology
- Pharmacology
- Health Outcomes Research
Background:
- Medication adherence is crucial for managing cardiovascular disease (CVD).
- Poor adherence negatively impacts prognosis and increases mortality risk.
- Reliable measurement tools are needed to identify non-adherence early.
Purpose of the Study:
- To identify high-quality, self-reported medication adherence tools for adults with CVD.
- To support improved health outcomes through better adherence measurement.
Main Methods:
- Systematic review of studies on self-reported adherence tools for CVD patients.
- Inclusion of adults (18+) with CVD, measuring initiation, implementation, or discontinuation.
- Searched multiple databases (PubMed, MEDLINE, etc.) across all languages and dates.
Main Results:
- Data synthesis focused on the quality of methods and measurement properties of adherence tools.
- Extensive database searches were conducted to ensure comprehensive identification of relevant studies.
Conclusions:
- Validated self-reported tools are essential for assessing medication adherence in cardiovascular patients.
- Accurate adherence measurement can guide interventions to improve clinical outcomes.
Objective:
The aim of this review is to identify high-quality, self-reported medication adherence tools for adults with cardiovascular disease to improve health outcomes.
Introduction:
Medication adherence is a complex concept affected by multiple factors and positively associated with clinical outcomes. Poor adherence to cardiovascular medications is a hindrance to the effective management of cardiovascular disease, leading to poor disease prognosis or increased risk of death. Valid and reliable measurement is crucial to identify patients with poor adherence, preferably before an adverse outcome occurs.
Inclusion Criteria:
This review will consider studies that include adults, aged 18 years and over, with a diagnosis of cardiovascular disease. The construct of medication adherence has three phases: initiation, implementation and discontinuation. Included tools need to measure at least one of these phases. The review will consider studies of any study design that report on the measurement properties of self-reported medication adherence tools among adults with cardiovascular disease.
Methods:
The following databases will be searched from inception to present: PubMed, MEDLINE, CINAHL, ProQuest Health and Medicine, Cochrane Library, PsycINFO, Scopus, Embase and Web of Science. Articles published in any language will be included, with no date limit. Data extraction will be performed by one reviewer and cross-checked by another reviewer. Data from the included studies will be synthesized using tables for the quality of methods, and measurement property results.
Systematic Review Registration Number:
PROSPERO CRD42019124291.
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