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[Malaria in childhood. Report of 26 cases]

M J Cilleruelo Ortega1, M J Mellado Peña, G Barreiro Casal

  • 1Servicio de Pediatría, Instituto Nacional Carlos III, Madrid.

Insights

Imported malaria cases in children are rising globally, with new chloroquine-resistant Plasmodium falciparum strains emerging in previously unaffected areas of Spain. This highlights the urgent need for updated malaria prevention and treatment strategies.

Area of Science:

  • Tropical medicine
  • Pediatric infectious diseases
  • Global health epidemiology

Context:

  • Global resurgence of malaria cases.
  • Increasing incidence of imported malaria in pediatric populations within Spain.
  • Emergence of Plasmodium falciparum strains resistant to chloroquine in previously non-resistant regions.

Purpose:

  • To highlight the rise in imported malaria cases among children in Spain.
  • To present clinical cases of Plasmodium falciparum malaria resistant to chloroquine in pediatric patients.
  • To review current treatment and prophylaxis guidelines for malaria.

Summary:

  • A clinical study and literature review focusing on imported malaria in Spanish children.
  • Documentation of three pediatric cases infected with chloroquine-resistant Plasmodium falciparum from areas recently identified as resistant.
  • Revision of global malaria prevention and primary healthcare strategies.

Impact:

  • Informs clinicians about the changing patterns of drug resistance in imported malaria.
  • Underscores the need for updated diagnostic and treatment protocols for pediatric malaria.
  • Contributes to global efforts in malaria control and elimination by highlighting emerging resistance threats.

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