Current status of radioligand antibodies in the treatment of malignancy
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A W Maners1, M M Sanders, A A Pappas
1Division of Radiation Therapy, University of Arkansas for Medical Sciences, Little Rock 72205.
Annals of Clinical and Laboratory Science
|January 1, 1988
Abstract:
Monoclonal anti-tumor antibodies labeled with a radioactive moiety present an exciting new approach to cancer therapy. With the advent of hybridoma technology, monoclonal antibodies can now be produced in quantity. Indeed, antibodies against tumor-related and tumor-specific antigens have been produced, labeled with a radioactive substance, and used therapeutically. The rationale for this therapeutic approach and the results of human clinical trials will be reported herein.