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Updated: Jul 7, 2026

Zika Virus Specific Diagnostic Epitope Discovery
Published on: December 12, 2017
Diagnostic Limitations in Congenital Zika Virus Infection
M Flanagan1, H Hughes2, E B Forman3
1Neonatology Department, National Maternity Hospital, Holles St, Dublin.
This is the first documented case of an infant with congenital Zika virus infection (ZVI) born in Ireland. A term infant was delivered with an antenatal diagnosis of severe microcephaly. First trimester bloods confirmed maternal ZVI and although the infant did not have Zika virus RNA or Zika-specific IgM in her blood or urine, she had multiple clinical features of congenital ZVI and Zika virus RNA was present in the placenta.
This is the first documented case of an infant with congenital Zika virus infection (ZVI) born in Ireland. A term infant was delivered with an antenatal diagnosis of severe microcephaly. First trimester bloods confirmed maternal ZVI and although the infant did not have Zika virus RNA or Zika-specific IgM in her blood or urine, she had multiple clinical features of congenital ZVI and Zika virus RNA was present in the placenta.
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