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Frailty Index: A Useful Stratification for Elderly Surgical Patients

P Rohan1, M K O'Reilly2, G J Nason3

  • 1Department of Surgery, Wexford General Hospital, Wexford, Ireland.

Irish Medical Journal
|August 21, 2020
PubMed
Abstract

No abstract available in PubMed .

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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