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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

Ahmed Sadik1, Luis F Somarribas Patterson2, Selcen Öztürk3

  • 1DKTK Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Faculty of Bioscience, Heidelberg University, 69120 Heidelberg, Germany.

Cell
|August 21, 2020
PubMed

Keywords:
AHRCLLIL4I1T cell exhaustionadaptive immunityaryl hydrocarbon receptorinterleukin 4 induced 1kynurenic acidtryptophan metabolismtumor micro-environment

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