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Psychological factors affecting Marfan syndrome patients with or without cardiac surgery

Miklós Pólos1, Kálmán Benke2, Bence Ágg3

  • 1Heart and Vascular Center, Semmelweis University, Budapest, Hungary; Hungarian Marfan Foundation, Budapest, Hungary. miklospolos@gmail.com.

Annals of Palliative Medicine
|August 22, 2020
PubMed
Abstract

Insights

Marfan syndrome patients experience unique psychosocial challenges, including sleep disturbances and pain, despite reporting higher life satisfaction. Integrating psychological support is crucial for comprehensive Marfan syndrome management.

Area of Science:

  • Medical research
  • Psychology
  • Genetics

Background:

  • Marfan syndrome (MFS) is a rare, systemic connective tissue disorder.
  • MFS patients face significant psychological distress impacting quality of life.
  • This study aimed to assess psychosocial aspects of MFS for improved patient management.

Purpose of the Study:

  • Evaluate psychological and psychosocial factors in Marfan syndrome patients.
  • Identify strategies to enhance disease management for MFS individuals.
  • Compare MFS patient well-being to the general Hungarian population.

Main Methods:

  • Prospective study of 66 adult Marfan syndrome patients (operated vs. non-operated).
  • Utilized multiple questionnaire tests for mental and physical state assessment.
  • Compared MFS patient data with a propensity-matched Hungarian population (Hungarostudy).

Main Results:

  • Marfan syndrome patients reported moderate pain disability, mild depressive symptoms, and sleep disturbances compared to the general population.
  • Despite challenges, MFS patients reported higher life satisfaction and happiness.
  • Operated patients showed higher alcohol consumption; non-operated patients had more sleep disturbances.

Conclusions:

  • Marfan syndrome patients exhibit distinct psychosocial profiles, including sleep issues and pain, compared to the general population.
  • A healthier lifestyle was observed in MFS patients regarding smoking.
  • Multidisciplinary MFS management should incorporate psychosocial assessment and support alongside medical treatments.
Keywords:
Marfan syndrome (MFS)anxietydepressionpain

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