Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The defective luteal phase.

P G Crosignani1

  • 1III Department of Obstetrics and Gynaecology, University of Milan, Italy.

Human Reproduction (Oxford, England)
|February 1, 1988
PubMed
Summary
This summary is machine-generated.

A defective luteal phase (DLP) is a progesterone deficiency affecting fertility. Plasma progesterone levels can help diagnose DLP, offering a less invasive alternative to endometrial biopsy for assessing corpus luteum function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Human papillomavirus testing versus multivariate tree analysis of demographic data in the triage of patients with mild cytological dysplasia.

Journal of lower genital tract disease·2015
Same author

High levels of women's satisfaction and compliance with transdermal contraception: results from a European multinational, 6-month study.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2010
Same author

The effect of surgery for symptomatic endometriosis: the other side of the story.

Human reproduction update·2009
Same author

Asymmetry in distribution of diaphragmatic endometriotic lesions: evidence in favour of the menstrual reflux theory.

Human reproduction (Oxford, England)·2007
Same author

Fibroids and female reproduction: a critical analysis of the evidence.

Human reproduction update·2007
Same author

Endometrial bleeding.

Human reproduction update·2007
Same journal

Characterizing endometriosis and adenomyosis symptom clusters and their impact on quality of life in the All of Us Research Program.

Human reproduction (Oxford, England)·2026
Same journal

A new regulatory framework: impact of the SoHO Regulation for medically assisted reproduction.

Human reproduction (Oxford, England)·2026
Same journal

Subfertility in relation to gestational weight gain and gestational diabetes: the Norwegian Mother, Father and Child Cohort Study.

Human reproduction (Oxford, England)·2026
Same journal

Pathogenic variants in ACTRT3 lead to male infertility characterized by fertilization defects.

Human reproduction (Oxford, England)·2026
Same journal

A large retrospective study on 1PN embryo transfer supports the need for updated harmonized best practice guidelines.

Human reproduction (Oxford, England)·2026
Same journal

Explainability of artificial intelligence (AI) tools in assisted reproductive technologies (ARTs): promise, clinical reality, and conceptual limits.

Human reproduction (Oxford, England)·2026
See all related articles

Area of Science:

  • Reproductive Endocrinology
  • Infertility Research

Background:

  • A defective luteal phase (DLP) is characterized by insufficient progesterone secretion from the corpus luteum.
  • While occasional DLPs occur in normal women, recurrent DLP is found in 7-14% of infertile patients.

Purpose of the Study:

  • To evaluate plasma progesterone levels as a diagnostic tool for inadequate luteal phase.
  • To explore alternatives to endometrial biopsy for diagnosing DLP.

Main Methods:

  • Review of diagnostic criteria for DLP.
  • Analysis of plasma progesterone levels in the luteal phase.

Main Results:

  • A single plasma progesterone level of 10 ng/ml or a mean concentration of 12-13 ng/ml over 4 days in the mid-luteal phase can exclude corpus luteum inadequacy.

Related Experiment Videos

  • Endometrial biopsy, though classical, is invasive and costly.

    • Conclusions:

    • Plasma progesterone measurement offers a viable, less invasive method to rule out inadequate luteal phase.
    • Further research is needed for 'essential' DLP to establish its role in infertility and therapeutic value.