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Related Experiment Videos

Eighty consecutive cases of gamete intra-fallopian transfer.

P C Wong1, S C Ng, M P Hamilton

  • 1Department of Obstetrics and Gynaecology, National University Hospital, Republic of Singapore.

Human Reproduction (Oxford, England)
|February 1, 1988
PubMed
Summary
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Gamete intra-Fallopian transfer (GIFT) achieved a 31.2% clinical pregnancy rate in 80 patients with infertility. This study highlights GIFT

Area of Science:

  • Reproductive Medicine
  • Infertility Treatment

Background:

  • Unexplained infertility, oligospermia, and endometriosis are significant causes of conception difficulties.
  • Gamete intra-Fallopian transfer (GIFT) is a recognized assisted reproductive technology.

Purpose of the Study:

  • To evaluate the efficacy of GIFT in patients with unexplained infertility, oligospermia, and endometriosis.
  • To determine pregnancy and multiple pregnancy rates associated with GIFT.
  • To assess the impact of oocyte transfer numbers on GIFT outcomes.

Main Methods:

  • Eighty patients underwent 80 cycles of GIFT for infertility.
  • Pregnancy outcomes, including clinical and biochemical pregnancies, multiple pregnancies, and miscarriages, were recorded.
  • Pregnancy rates were analyzed based on the underlying cause of infertility.

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Main Results:

  • A clinical pregnancy rate of 31.2% (25/80) was achieved.
  • The overall conception rate was 36.3% (29/80).
  • Pregnancy rates varied by condition: 33.3% for unexplained infertility, 16.7% for oligospermia, and 38.5% for endometriosis.

Conclusions:

  • GIFT demonstrates a viable clinical pregnancy rate for patients with infertility.
  • Transferring four oocytes may enhance pregnancy rates without increasing multiple pregnancy risk.
  • Excess oocyte in-vitro fertilization did not correlate with GIFT success.