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Related Experiment Video

Updated: Dec 11, 2025

Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
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Successful use of problem-solving methodology to reduce pharmacy chemotherapy processing time.

Glenn Fonte, Jordan Bolooki, Lauren N Gjolaj

    Journal of the American Pharmacists Association : Japha
    |August 22, 2020
    PubMed
    Summary

    A new Concierge initiative significantly reduced pharmacy turnaround time and patient wait times for chemotherapy services. This approach improved workflow and capacity, allowing more patients to be treated daily without compromising safety or quality.

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    Area of Science:

    • Pharmacy Practice
    • Healthcare Operations
    • Quality Improvement

    Background:

    • Hospital pharmacies face challenges with high compounded chemotherapy order volumes, leading to staff overload during peak hours.
    • This overload contributes significantly to extended patient wait times and impacts overall pharmacy turnaround time (TAT).

    Purpose of the Study:

    • To reduce pharmacy turnaround time (TAT) and compounding order overload during peak hours.
    • To decrease patient wait times for pharmacy services without compromising safety and quality.

    Main Methods:

    • Implementation of a "Concierge" initiative involving advanced preparation of chemotherapy for select patients.
    • Utilized Define Measure Analyze Improve Control (DMAIC) Six Sigma methodology and intelligent risk-taking strategies to identify and address root causes.

    Main Results:

    • Pharmacy TAT decreased by 77% for Concierge patients and 31% for standard patients.
    • Patient wait time decreased by 67% for Concierge patients and 27% for standard patients.
    • Observed an 8% increase in patient capacity despite no changes in physical infrastructure.

    Conclusions:

    • The Concierge initiative markedly reduced pharmacy TAT and patient wait times, particularly for chemotherapy services.
    • Improved workflow efficiency and staff assignment distribution, leading to decreased order overload and enhanced patient throughput.
    • Successfully maintained safety and quality standards while increasing the number of patients treated daily.