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Moving towards ideal and appropriate models of anticoagulation management service
1Department of Medicine; Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Nigeria Enugu Campus, Dedicated Anticoagulation Clinic, University of Nigeria Teaching Hospital, Enugu, Nigeria.
Insights
New anticoagulation models are essential to manage thrombotic disorders effectively. Restructuring services ensures safer, more accessible, and cost-effective patient care, especially with novel oral anticoagulants.
Area of Science:
- Cardiology
- Pharmacology
- Health Services Research
Background:
- Thrombotic disorders like venous thromboembolism, ischemic stroke, and myocardial infarction are major global health issues.
- Warfarin, a traditional anticoagulant, has limitations, while non-vitamin K oral anticoagulants (NOACs) present new challenges.
- Current anticoagulation services require adaptation to address these evolving clinical needs.
Purpose of the Study:
- To discuss the development of appropriate anticoagulation service models.
- To address the drawbacks of older anticoagulants and improve the compliance, availability, affordability, and accessibility of newer agents.
- To highlight the need for restructuring anticoagulation services in the era of NOACs.
Main Methods:
- The article reviews existing anticoagulation practices and proposes new service models.
- It emphasizes the importance of a triad: rational drug prescription, therapy monitoring via anticoagulation clinics, and active patient participation.
- It advocates for multidisciplinary teams including physicians, pharmacists, clinical pharmacologists, nurses, and laboratory scientists.
Main Results:
- Optimal anticoagulation requires balancing thrombosis risk and hemorrhage complications.
- New service models can be developed from the physician, clinic, and patient factors.
- Restructuring is crucial for safe, efficacious, and cost-effective anticoagulation management.
Conclusions:
- The evolution of anticoagulants necessitates innovative service delivery models.
- Appropriately trained professionals are vital for effective anticoagulation management.
- New models are needed to ensure safe, effective, and cost-efficient anticoagulation services, particularly with NOACs.
Abstract:
It is now known that thrombotic disorders such as venous thromboembolism, ischemic stroke, and myocardial infarction contribute significantly to global morbidity and mortality. Anticoagulation service must respond to this new development. Warfarin has continued to provide the backbone for anticoagulation service for decades but with considerable drawbacks. The introduction of nonVitamin K oral anticoagulants (NOACs) has created new challenges. This article seeks to discuss how the establishment of appropriate models of anticoagulation could contain the draw backs of the old anticoagulants and improve on the compliance, availability, affordability, and accessibility of newer anticoagulants. Successful anticoagulation has always been defined by a scientific balancing of the risk of thrombosis and the complication of hemorrhage. To be able to maintain such optimal anticoagulation requires rational drug prescription (physician factor), institutelization of monitoring of therapy (anticoagulation clinic factor) as well as active participation of patients receiving therapy (patient factor). New models of service can be created out of this triad in a bid to replace the old routine medical care model. New models of anticoagulation service should include appropriately trained professionals such as Physicians, Pharmacists, Clinical Pharmacologists, Nurses, and Laboratory Scientists who are knowledgeable in diagnostic, management, and monitoring of anticoagulation. The different models of anticoagulation service discussed in this article clearly demonstrate the need for restructuring of this life saving service particularly in the era of NOAC. Newer models of care that should provide safe, efficacious, and cost-effective services are needed.
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