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Updated: Dec 11, 2025

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
Demographic pattern of chronic lymphocytic leukemia in a tertiary hospital in Calabar, South-South Nigeria
Kingsley Akaba1, Ofem Enang2, Hilary Igwilo1
1Department of Haematology and Blood Transfusion, University of Calabar Teaching Hospital, Calabar, Nigeria.
Background:
Chronic lymphocytic leukemia (CLL) is a heterogeneous group of monoclonal forms of lymphoproliferative disorder, which is usually common among older adults. There is an increasing trend in the number of patients presenting with the disease.
Aim:
This study aims to determine the epidemiology pattern of CLL in Cross River state.
Methodology:
A retrospective study with 10-years data (2010-2019) obtained from the register of the Department of Haematology and Blood Transfusion, University of Calabar Teaching Hospital, Calabar. The data collected include the date of presentation, the age, gender, location of residence, and occupations of the patients.
Results:
A total of 47 cases were seen during the 10-year period, with a male: female ratio of 1:1. The mean age at presentation was 59 years. The majority of the patients were in their fifth and sixth decades of life. Most patients (44.68%) practice farming as their profession.
Conclusion:
The study has reawaken our consciousness on the increasing trend on the epidemiological burden of CLL in our environment and will help to enhance further investigation into the relationship between the rising trend and available possible risk factors in our environment.
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