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Updated: Dec 11, 2025
Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
Published on: October 20, 2011
Modified Papanicolaou staining for oral swab samples stored long term
Srijayaprakash B Uppada1,2, Lepakshi S V Madduri1, Sravani Singu1
1Department of Pharmacology and Experimental Neuroscience, Durham Research Center, University of Nebraska Medical Center, Omaha, Nebraska.
Abstract:
Pathologists collect swab samples for Papanicolaou (Pap) staining to diagnose various diseases including cancer and HIV. Time constraints and limited resources, may preclude staining a sample immediately. To re-confirm results, samples must be frozen for later analysis. We present a method for Pap staining cells that have been stored long term. An effective method for Pap staining of frozen cells should enable flexibility for processing samples.
