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Updated: Dec 11, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Splenic Infarct Secondary to High Altitude Exposure in Sickle Cell Trait Patients: A Case Series
Luis Gonzalez1, Andres F Shapiro2, Alfonso Tafur3
1Medicine, Nassau University Medical Center, East Meadow, USA.
Abstract:
The sickle cell trait is considered a benign entity that generally does not show clinical manifestations. However, some complications have been described under certain conditions, such as a decrease in oxygen level, dehydration, and strenuous physical efforts. Among them, splenic infarct is a rare complication that presents as left upper abdominal pain in a situation of stress such as high altitude exposure. We present two cases of splenic infarcts in patients with undiagnosed sickle cell trait who showed to our institution with severe abdominal pain after coming from high altitude cities.
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