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70K heat shock related proteins stimulate protein translocation into microsomes
W J Chirico1, M G Waters, G Blobel
1Laboratory of Cell Biology, Howard Hughes Medical Institute, Rockefeller University, New York, New York 10021.
Nature
|April 28, 1988
Abstract:
A yeast cytosol is shown to contain two distinct activities that stimulate protein translocation across microsomal membranes. One activity was purified. It consists of two constitutively expressed 70K heat shock related proteins that increase the rate of translocation. Possible mechanisms of action of these proteins are discussed.