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Related Experiment Video

Updated: Dec 11, 2025

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
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Choroidal thickness changes in patients with diabetes

Hajnalka Horváth1, Mónika Ecsedy1, Illés Kovács1

  • 1Általános Orvostudományi Kar, Szemészeti Klinika,Semmelweis Egyetem, Budapest.

Orvosi Hetilap
|August 22, 2020
PubMed
Summary

Diabetic retinopathy significantly thins the choroid, a finding linked to diabetes duration, hypertension, and advanced disease stages. Panretinal photocoagulation also correlates with reduced choroidal thickness.

Keywords:
chorioideavastagságchoroidal thicknessdiabeteses retinopathiadiabetic retinopathyswept source optikaikoherencia-tomográfiaswept-source optical coherence tomography

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Area of Science:

  • Ophthalmology
  • Diabetology
  • Medical Imaging

Background:

  • Diabetic retinopathy (DR) is a leading cause of vision loss.
  • The role of the choroid in DR pathogenesis is increasingly recognized.
  • Swept-source optical coherence tomography (SS-OCT) offers advanced non-invasive imaging of the choroid.

Purpose of the Study:

  • To measure choroidal thickness in diabetic patients using SS-OCT.
  • To correlate choroidal thickness with diabetes duration, systemic risk factors, and DR severity/therapy.
  • To elucidate the impact of diabetes and its complications on choroidal structure.

Main Methods:

  • Prospective cross-sectional study involving 117 diabetic eyes and 45 healthy control eyes.
  • Choroidal and macular thickness measured using SS-OCT.
  • Statistical analysis (multiple regression) to evaluate correlations between choroidal thickness and clinical parameters.

Main Results:

  • Diabetic patients exhibited significantly thinner choroids compared to controls (p<0.05).
  • Choroidal thinning correlated with aging, hypertension, and longer diabetes duration.
  • Prognostic factors for thinner choroids included proliferative diabetic retinopathy and panretinal photocoagulation treatment.

Conclusions:

  • Diabetes mellitus and DR progression significantly impact choroidal thickness.
  • Systemic factors like age, hypertension, and disease duration are key predictors of choroidal thinning.
  • Choroidal thinning is associated with advanced DR treatments such as panretinal photocoagulation.