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Migratory serpiginous corneal epitheliopathy (MSCE)- details of 4 cases
Amrita Mohanty1, Ruchi Mittal2, Ashi Khurana3
1Cornea and Anterior Segment Services, L. V. Prasad Eye Institute, Bhubaneswar, Odisha, India.
Background And Objective:
To describe four cases of recurrent, fleeting corneal epithelial lesion, migratory serpiginous corneal epitheliopathy (MSCE).
Method:
Description of cases, histopathology and discussion of treatment outcome.
Results:
The study included 4 consecutive male patients; mean age was 21.25 years. Only one eye was affected. The common symptoms were irritation and tearing. Typical interpalpebral corneal lesion was a superficial greyish-white elevated corneal epithelium with stippled fluorescein staining in various geographic patterns. Corneal scrapings did not show any microorganisms and culture was negative; histopathology did not show corneal dysplasia. The lesions recurred within 1-3 weeks despite repeated scraping, application of a bandage contact lens, and a combination of topical antibiotics and lubricants. The recurrent lesion was of a different shape and eventually healed within 3-6 months without scarring.
Conclusion:
We describe a possibly new entity, unilateral migratory serpiginous corneal epitheliopathy (MSCE) affecting young males, with inconspicuous inflammation. Etiology is not known and usually takes several months to heal after repeated epithelial debridement.
