Related Experiment Video

Updated: Dec 11, 2025

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
07:10

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

10.1K

Exercise capacity in children with bronchopulmonary dysplasia at school age

Freerk Prenzel1, Mandy Vogel2, Werner Siekmeyer1

  • 1University of Leipzig Medical Center, Department of Pediatrics and Center for Pediatric Research Leipzig, Liebigstr. 20a, 04103, Leipzig, Germany.

Respiratory Medicine
|August 22, 2020
PubMed

Insights

Children with bronchopulmonary dysplasia (BPD) experience reduced exercise capacity and lung function at school age. They also report more exercise-related respiratory symptoms compared to healthy peers.

Area of Science:

  • Pediatric Pulmonology
  • Exercise Physiology
  • Neonatology

Background:

  • Bronchopulmonary dysplasia (BPD) is a chronic lung disease affecting preterm infants.
  • Long-term effects of BPD on exercise capacity and lung function at school age are not fully understood.

Purpose of the Study:

  • To compare exercise capacity, exercise habits, and lung function in school-aged children with BPD versus term-born controls.
  • To identify potential exercise limitations and respiratory symptoms in children with BPD.

Main Methods:

  • Cardiopulmonary exercise testing (CPET) and pulmonary function tests were conducted in 42 children with BPD and 42 controls.
  • Questionnaires assessed daily activity, sports participation, and respiratory symptoms.

Main Results:

  • Children with BPD demonstrated significantly lower peak exercise oxygen consumption, minute ventilation, and workload compared to controls.
  • Reduced forced expiratory volume in 1 second and expiratory flow were observed in the BPD group.
  • Children with BPD reported increased difficulties with physical activity and exercise-induced wheezing or shortness of breath.

Conclusions:

  • School-aged children with BPD exhibit airflow obstruction and reduced exercise capacity.
  • They experience more respiratory symptoms during physical activity.
  • Weight-adjusted oxygen consumption suggests preserved alveolar function despite airflow limitations.
Abstract

Keywords:
Cardiopulmonary exercise testCycle ergometryLung functionPretermRespiratory symptomsVery low birth weight

More Related Videos

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.1K
Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

6.1K

Related Concept Videos

Lung Capacity01:47

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
55.6K
Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
604
Respiratory Capacities01:24

Respiratory Capacities

Respiratory capacities are crucial indicators of lung function, representing the maximum amount of air an individual's respiratory system can handle during various breathing phases.
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
1.2K
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
612
Respiratory Volumes and Capacities I01:26

Respiratory Volumes and Capacities I

Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...
1.4K
Respiratory Volumes and Capacities01:22

Respiratory Volumes and Capacities

The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...
4.4K