Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.2K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.2K
Nursing Clinical Information System01:27

Nursing Clinical Information System

1.1K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.1K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

307
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
307
Ethics in Research01:56

Ethics in Research

25.2K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.2K
Health Information Technology and Healthcare Information System01:30

Health Information Technology and Healthcare Information System

1.2K
Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
1.2K
Clinical Trials01:16

Clinical Trials

10.1K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Addressing Data Quality Challenges in Lung Cancer Data Within the Observational Medical Outcomes Partnership Common Data Model: Observational Study.

Journal of medical Internet research·2026
Same author

Building an Ontology-Based Cohort of Liver Cancer Imaging Data for AI Development on the European Federated Platform EUCAIM.

Studies in health technology and informatics·2026
Same author

Reuse of EUCAIM Ontology for Prescreening Use Case.

Studies in health technology and informatics·2026
Same author

Standardizing ICU Data Across Europe: Development of the INDICATE Minimal Data Dictionary.

Studies in health technology and informatics·2026
Same author

Assessment of the ADLIFE intervention as a digital solution for patients with advanced chronic diseases: a quasi-experimental trial.

NPJ digital medicine·2026
Same author

Rethinking Trust in Synthetic Health Data: Lessons From 7 European Research Initiatives.

Journal of medical Internet research·2026
Same journal

Citizens' Options When Accessing and Sharing Health Information - An International Survey of IMIA Member Countries.

Yearbook of medical informatics·2025
Same journal

Social Determinants of Health in Digital Health Policies: an International Environmental Scan.

Yearbook of medical informatics·2025
Same journal

Sensors, Signals, and Imaging Informatics: Best contributions from 2023.

Yearbook of medical informatics·2025
Same journal

Alzheimer Disease Detection Studies: Perspective on Multi-Modal Data.

Yearbook of medical informatics·2025
Same journal

Exploring the Latest Advances in Public Health and Epidemiology Informatics.

Yearbook of medical informatics·2025
Same journal

Application of Digital Informatics in Precision Prevention, Epidemiology, and Clinicogenomics Research to Advance Precision Healthcare.

Yearbook of medical informatics·2025
See all related articles

Related Experiment Video

Updated: Dec 11, 2025

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.1K

Clinical Research Informatics.

Christel Daniel1,2, Dipak Kalra3,

  • 1Information Technology Department, AP-HP, Paris, France.

Yearbook of Medical Informatics
|August 22, 2020
PubMed
Summary
This summary is machine-generated.

Clinical Research Informatics (CRI) research in 2019 focused on real-world evidence and electronic health record (EHR) data reuse. Key papers highlight secure data analysis, federated networks, and improved pharmacovigilance through data integration.

More Related Videos

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.5K
Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.5K

Related Experiment Videos

Last Updated: Dec 11, 2025

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.1K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.5K
Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.5K

Area of Science:

  • Clinical Research Informatics (CRI)
  • Health Data Science
  • Biomedical Informatics

Background:

  • Clinical Research Informatics (CRI) is crucial for advancing medical research.
  • Identifying significant contributions in CRI is essential for guiding future research directions.
  • 2019 saw notable advancements in the accessibility and reusability of real-world data (RWD).

Purpose of the Study:

  • To summarize key contributions in Clinical Research Informatics (CRI) from 2019.
  • To identify and highlight the three best papers published in the field during 2019.
  • To provide insights into current trends and future research avenues in CRI.

Main Methods:

  • Bibliographic search of CRI literature in PubMed using MeSH and free-text terms.
  • Double-blind review process to select candidate papers.
  • External peer review and consensus meeting to finalize the selection of the top three papers.

Main Results:

  • Three best papers were selected from 517 articles published in 2019.
  • Selected papers cover homomorphic encryption for federated RWD analysis, federated networks for hypertension treatment studies, and migration of FDA adverse event data to OMOP CDM for enhanced pharmacovigilance.
  • These papers showcase advancements in data privacy, real-world evidence (RWE) generation, and data integration for pharmacovigilance.

Conclusions:

  • Current CRI research emphasizes RWE generation and electronic health record (EHR) data reuse.
  • Progress in phenotyping, data integration, interoperability, and quality assessment enhances RWD accessibility.
  • Data governance, security, confidentiality, and ethical/regulatory issues remain active research areas.