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Related Experiment Video

Updated: Dec 11, 2025

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Relationship between Diet, Microbiota, and Healthy Aging.

Elisa Sanchez-Morate1, Lucia Gimeno-Mallench1,2, Kristine Stromsnes1

  • 1Freshage Research Group, Department of Physiology, Faculty of Medicine, University of Valencia, CIBERFES-ISCIII, INCLIVA, 46010 Valencia, Spain.

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Summary

Achieving healthy aging involves modulating the gut microbiota through diet. Nutrition, rich in fiber and polyphenols, and low in fat, supports beneficial gut bacteria for overall health.

Keywords:
Mediterranean dietOriental dietaginghealthmicrobiotanutritionpolyphenols

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Area of Science:

  • Gerontology and Nutritional Science
  • Microbiome Research

Background:

  • Increased life expectancy necessitates strategies for healthy aging.
  • Age-related diseases and damage require risk factor reduction.
  • Nutrition is a key pillar for health and disease prevention.

Purpose of the Study:

  • To explore the role of nutrition in promoting healthy aging.
  • To investigate the impact of dietary modulation on the gut microbiota.
  • To highlight the benefits of specific dietary components and patterns.

Main Methods:

  • Review of existing literature on nutrition, aging, and gut microbiota.
  • Analysis of dietary patterns like Mediterranean and Oriental diets.
  • Examination of the role of dietary fiber and polyphenols.

Main Results:

  • Dietary interventions can modulate the gut microbiota composition and function.
  • Fiber and polyphenols, abundant in certain diets, promote beneficial gut bacteria.
  • Reduced intake of high-fat products positively influences microbiota health.

Conclusions:

  • Dietary strategies targeting the gut microbiota are crucial for healthy aging.
  • Incorporating fiber-rich and polyphenol-rich foods supports a healthy microbiome.
  • Limiting high-fat foods contributes to improved gut health and overall well-being.