Related Experiment Video
Updated: Dec 11, 2025

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
Published on: May 10, 2017
Treatment of panic disorder by trigeminal nerve manipulation: A case series
Emmanuel Birstein1, Judith Gusky1
1Pittsburgh Integrative Mental Health, 160 N. Craig St. Suite 212 Pittsburgh, PA, 15213, USA.
Abstract:
This is a report on two cases of patients with acute severe panic disorder relieved of their symptoms by manual manipulations of the trigeminal nerve's alveolar branches. The manipulations were performed via the oral cavity during one session, or two consecutive sessions less than a week apart. No other effective treatment was administered prior, concurrently or since the time of the treatment. The recovery from panic disorder was immediate and lasted for the entire period of observation of three years. The authors used the same procedure and achieved identical clinical results treating ten other clients over a period of three years. This was not a planned experiment or randomized study. Rather, this report presents clinical evidence and the authors' hypothesis based on clinical data and literature review.

