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Circadian patterns in coronary disease: the mournfulness of morning

P Bogaty1, D D Waters

  • 1Department of Medicine, Montreal Heart Institute, Quebec.

The Canadian Journal of Cardiology
|January 1, 1988
PubMed

Insights

Coronary artery disease events like angina, myocardial infarction, and sudden cardiac death show a circadian pattern. These cardiovascular events peak in the morning, suggesting a daily rhythm influences disease manifestation.

Area of Science:

  • Cardiology
  • Chronobiology
  • Internal Medicine

Background:

  • Circadian rhythms influence physiological processes.
  • Cardiovascular diseases exhibit temporal patterns.

Purpose of the Study:

  • To review the circadian patterns of coronary artery disease manifestations.
  • To identify peak incidence times for different cardiac events.

Main Methods:

  • Literature review of studies on coronary artery disease and circadian rhythms.
  • Analysis of reported incidence patterns for angina, myocardial infarction, and sudden cardiac death.

Main Results:

  • All reviewed coronary artery disease manifestations demonstrate a circadian pattern.
  • Typical angina, myocardial infarction, and sudden cardiac death peak between 06:00 and noon.
  • Variant angina shows an earlier peak incidence, from midnight to 09:00.

Conclusions:

  • A daily rhythm significantly impacts the occurrence of coronary artery disease.
  • Understanding these circadian patterns may aid in preventative strategies and treatment timing for cardiovascular events.

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