The genetic origins of human cancer

Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.

Oncogene·2014

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence.

Oncogene·2010

The evolving portrait of cancer metastasis.

Cold Spring Harbor symposia on quantitative biology·2006

Derivation of human tumor cells in vitro without widespread genomic instability.

Cancer research·2001

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

Cell·2001

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.

Nature cell biology·2001

Long-term patient-reported outcomes and toxicity following salvage radiotherapy for biochemical recurrence after radical prostatectomy.

Cancer·2026

Prognostic stratification of patients with biliary tract cancer treated with chemoimmunotherapy: A retrospective multicenter real-world study.

Cancer·2026

IMMU-NO versus yes: Applicability of immune checkpoint inhibitors in gynecologic cancers.

Cancer·2026

Effect of demographic characteristics on the outcome of prostate cancer salvage radiotherapy: Analysis from a randomized controlled trial.

Cancer·2026

Timing matters: Impact of covalent BTK inhibitor dose modifications on outcomes in chronic lymphocytic leukemia/small lymphocytic leukemia-A 7-year real-world study.

Cancer·2026

Clinical management of clonal hematopoiesis.

Cancer·2026

Decoding the cancer microbiome: multi-omics, AI, and translational opportunities.

Genome biology·2026

From COPD and asthma to lung cancer: potential candidate genes and their associated biological pathways for the incidence risk of lung cancer.

Journal, genetic engineering & biotechnology·2026

A novel synonymous TSC2 mutation in a Chinese family leads to tuberous sclerosis type 2 by disrupting Normal pre-mRNA splicing.

Journal, genetic engineering & biotechnology·2026

Association of CYP2R1 gene polymorphisms with type 2 diabetes mellitus in the Jordanian population.

Journal, genetic engineering & biotechnology·2026

Evolutionary genomics, tumor dynamics, and mathematical modeling of cancer progression: Implications for precision oncology.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases·2026

Molecular epidemiological surveillance of the Feline Coronavirus reveals novel recombinant FCoV strains with evidence of ongoing viral evolution.

Virus research·2026

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The genetic origins of human cancer

Related Concept Videos

Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence.

The evolving portrait of cancer metastasis.

Derivation of human tumor cells in vitro without widespread genomic instability.

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.

Long-term patient-reported outcomes and toxicity following salvage radiotherapy for biochemical recurrence after radical prostatectomy.

Prognostic stratification of patients with biliary tract cancer treated with chemoimmunotherapy: A retrospective multicenter real-world study.

IMMU-NO versus yes: Applicability of immune checkpoint inhibitors in gynecologic cancers.

Effect of demographic characteristics on the outcome of prostate cancer salvage radiotherapy: Analysis from a randomized controlled trial.

Timing matters: Impact of covalent BTK inhibitor dose modifications on outcomes in chronic lymphocytic leukemia/small lymphocytic leukemia-A 7-year real-world study.

Clinical management of clonal hematopoiesis.

Decoding the cancer microbiome: multi-omics, AI, and translational opportunities.

From COPD and asthma to lung cancer: potential candidate genes and their associated biological pathways for the incidence risk of lung cancer.

A novel synonymous TSC2 mutation in a Chinese family leads to tuberous sclerosis type 2 by disrupting Normal pre-mRNA splicing.

Association of CYP2R1 gene polymorphisms with type 2 diabetes mellitus in the Jordanian population.

Evolutionary genomics, tumor dynamics, and mathematical modeling of cancer progression: Implications for precision oncology.

Molecular epidemiological surveillance of the Feline Coronavirus reveals novel recombinant FCoV strains with evidence of ongoing viral evolution.

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The genetic origins of human cancer

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