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Updated: Dec 11, 2025

Engineered Vascularized Muscle Flap
Published on: January 11, 2016
Muscle Flap Closure following Complex Spine Surgery: A Decade of Experience
Matthew A Wright1, Andrew L Weinstein1, Jaime L Bernstein1
1From the Division of Plastic Surgery, Department of Surgery, and the Department of Neurosurgery, Weill Cornell Medicine; and the Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University.
Immediate muscle flap closure is a safe and effective technique for complex spine surgery in high-risk patients, showing acceptable wound complication rates. This approach is recommended for carefully selected individuals undergoing spinal procedures.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Surgical Innovation
Background:
- Complex spine surgeries are increasing due to technological advances and an aging population.
- High-risk patients undergoing these procedures face elevated risks of surgical wound complications, with some studies reporting incidences up to 45%.
Purpose of the Study:
- To evaluate the efficacy and safety of immediate muscle flap closure in high-risk patients undergoing complex spine surgery.
- To identify predictors of major wound complications in this patient cohort.
Main Methods:
- A retrospective review of 301 consecutive index cases of spinal wound closure using local muscle flaps.
- Analysis of major wound complications (reoperation/readmission for infection, dehiscence, seroma, hematoma) and identification of risk factors using logistic regression.
Main Results:
- Major wound complications occurred in 6.6% of patients, with a 6.0% infection rate.
- Identified risk factors for complications included prior radiotherapy, age 65+, and previous spine surgery.
- No significant association was found between mean drain dwell duration and major wound complications.
Conclusions:
- Immediate local muscle flap closure is a safe and effective method for complex spine surgery in high-risk patients.
- The technique is associated with acceptable rates of wound complications.
- Consideration of immediate muscle flap closure is recommended for appropriately selected patients.
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