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A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
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Cardiovascular Risk Factors Following Vertical Sleeve Gastrectomy in Black Americans Compared with White Americans
Joshua S Speed1, William A Pruett2, Seth T Lirette3
1Department of Physiology and Biophysics, University of Mississippi Medical Center, 2500 North State St. Guyton 558, Jackson, MS, 39216, USA. jspeed@umc.edu.
Obesity Surgery
|August 23, 2020
Summary
Black Americans experienced less weight loss after sleeve gastrectomy (SG) but showed similar blood pressure improvements when normalized to weight loss compared to White Americans.
Area of Science:
- Bariatric Surgery
- Cardiovascular Health
- Health Disparities
Background:
- Obesity disproportionately affects Black Americans (BA), leading to greater comorbidity burden compared to White Americans (WA).
- Sleeve gastrectomy (SG) is a common bariatric surgery for obesity management.
- Understanding racial disparities in SG outcomes is crucial for equitable care.
Purpose of the Study:
- To quantify cardiovascular and lipid outcomes after SG.
- To investigate racial disparities in these outcomes between BA and WA.
- To assess the impact of SG on obesity comorbidities in diverse populations.
Main Methods:
- Retrospective analysis of de-identified electronic medical records from patients undergoing SG.
- Comparison of baseline characteristics and post-operative outcomes between BA and WA.
- Statistical analysis of body weight, blood pressure, and lipid profiles.
Main Results:
- BA had higher baseline body weight, BMI, and blood pressure than WA.
- WA experienced significantly greater reductions in systolic and diastolic blood pressure post-SG compared to BA.
- No significant racial differences were observed in changes to cholesterol or triglyceride levels.
- The disparity in blood pressure reduction between racial groups was mitigated when normalized to weight loss.
Conclusions:
- Black Americans tend to achieve less weight loss following sleeve gastrectomy compared to White Americans.
- Despite differences in weight loss, the improvement in blood pressure is similarly associated with excess weight loss in both racial groups.
- These findings highlight the need for tailored approaches to optimize bariatric surgery outcomes across different racial demographics.
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