[Probiotics intake as gut-microbiota modulating therapy in an interdisciplinary aspect]

Area of Science:

• Microbiology and Endocrinology
• Gut Microbiome Research
• Metabolic and Inflammatory Disorders

Background:

• The gut microbiota is recognized as an endocrine organ with significant metabolic capabilities.
• Microbiota imbalance is linked to metabolic, infectious, inflammatory, and stress-related disorders.
• Established links exist between gut microbiota and conditions like metabolic syndrome, IBD, and mental health disorders.

Purpose of the Study:

• To explore the role of gut microbiota in health and disease.
• To evaluate the potential of diet, probiotics, and prebiotics in modulating gut microbiota.
• To assess the therapeutic implications of microbiota modulation for various health conditions.

Main Methods:

• Review of scientific literature on gut microbiota composition and function.
• Analysis of studies investigating the impact of probiotic and prebiotic interventions.
• Examination of the relationship between gut microbiota and specific pathologies.

Main Results:

• Probiotic and prebiotic intake can favorably alter gut microbiota composition.
• Modulation of gut microbiota demonstrates beneficial effects in metabolic, endocrine, and mental disorders.
• Probiotics inhibit pathogens, reduce inflammation, and regulate immune activity.

Conclusions:

• Dietary interventions, particularly with probiotics, are effective in preventing and treating diseases.
• Maintaining gut epithelial barrier integrity through microbiota modulation is crucial for health.
• Probiotic supplementation can enhance treatment outcomes and protect against long-term health consequences.