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A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
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COVID-19 and Influenza Co-Infection: Report of Three Cases

Balraj Singh1, Parminder Kaur2, Ro-Jay Reid3

  • 1Hematology/Oncology, Saint Joseph's University Medical Center, Paterson, USA.

Cureus
|August 25, 2020
PubMed

Insights

Influenza and COVID-19 are distinct respiratory viruses. This study details three cases where patients were co-infected with both influenza and the virus causing COVID-19.

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Influenza and COVID-19 are significant global respiratory pathogens.
  • Both illnesses are caused by distinct viral agents: influenza viruses (A and B) and SARS-CoV-2.
  • Understanding co-infections is crucial for clinical management and epidemiology.

Observation:

  • Three cases of co-infection with influenza and COVID-19 were identified.
  • Patients presented with symptoms characteristic of respiratory viral infections.
  • Co-infection highlights the potential for simultaneous viral challenges.

Findings:

  • Co-infection with influenza and SARS-CoV-2 is possible.
  • The study documents specific instances of dual viral respiratory infections.
  • This finding underscores the need for differential diagnosis.

Implications:

  • Co-infection may lead to more severe disease presentations.
  • Diagnostic strategies should consider multiple respiratory viruses.
  • Public health interventions may need to address concurrent influenza and COVID-19 circulation.

Keywords:
co-infectioncoronaviruscovid-19fluinfluenzainfluenza virus type ainfluenza virus type binfluenza-like illnesssars-cov-2severe acute respiratory syndrome coronavirus 2

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