Related Experiment Video
Updated: Dec 11, 2025

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Evidence for a Causal Relationship Between Academic Achievement and Cigarette Smoking
Kenneth S Kendler1,2, Henrik Ohlsson3, Abigail A Fagan4
1Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA.
Higher academic achievement (AA) causally reduces smoking rates and increases smoking cessation in pregnant women. Improving educational attainment can significantly improve public health by reducing tobacco use.
Area of Science:
- Epidemiology
- Public Health
- Behavioral Science
Background:
- Academic achievement (AA) is known to be associated with smoking rates.
- The causal nature of this relationship requires further investigation.
Purpose of the Study:
- To determine the causal effect of academic achievement on smoking rates.
- To explore the impact of AA on smoking cessation in specific populations.
Main Methods:
- Instrumental variable (IV) analyses utilizing month-of-birth as an instrument for AA.
- Co-relative analyses using familial data (cousins, siblings) to control for confounding factors.
- Prediction of smoking in male conscripts and pregnant females based on AA.
Main Results:
- Higher AA was associated with a significant decrease in smoking risk in males (OR=0.41).
- Consistent evidence for a causal effect of AA on reduced smoking and increased cessation was found in pregnant females across different analytical methods.
- Specifically, for females smoking prior to pregnancy, AA predicted reduced continued smoking (ORs ranging from 0.54 to 0.78).
Conclusions:
- Higher academic achievement causally reduces smoking rates and increases smoking cessation in pregnant women.
- Interventions aimed at improving educational achievement in adolescence may lead to substantial public health gains through reduced tobacco consumption.
More Related Videos
Related Concept Videos
Criteria for Causality: Bradford Hill Criteria - I
Criteria for Causality: Bradford Hill Criteria - II
Statistical Methods for Analyzing Epidemiological Data
Stress Prevention and Stress Management Techniques IV
Causality in Epidemiology
Cause and Effect

