Related Experiment Video
Updated: Dec 11, 2025

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Roberts Syndrome With a Bilateral Cleft Lip and Palate
Geiza Máximo1, Cesar Augusto Raposo-Amaral1, Ana Beatriz Affonseca Paez1
1Institute of Plastic and Craniofacial Surgery, SOBRAPAR Hospital, Campinas.
Abstract:
Roberts syndrome (RBS) is a rare craniofacial anomaly associated with tetraphocomelia, growth and mental retardation, cardiac and renal abnormalities. The RBS is caused by homozygous mutation in the ESCO2 gene on chromosome 8p21. In this report, the authors describe a 5-year-old female infant with RBS and bilateral cleft lip and cleft palate, an extremely rare condition.
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