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Cerebrovascular disease in COVID-19: Is there a higher risk of stroke?

Marcos Altable1, Juan Moisés de la Serna2

  • 1Private Practice of Neurology, Neuroceuta. (Virgen de África Clinic), Ceuta, Spain.

Brain, Behavior, & Immunity - Health
|August 25, 2020
PubMed

Insights

COVID-19 is linked to stroke in young adults, even without typical risk factors. Further research is needed to understand the connection between COVID-19 infection and cerebrovascular events.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Cardiovascular Medicine

Background:

  • COVID-19 has been associated with stroke in young adults lacking traditional cardiovascular risk factors.
  • Cerebrovascular events are typically more prevalent in older individuals with risk factors like hypertension and diabetes.
  • There is a growing body of evidence suggesting hypercoagulability as a potential contributor to cerebral ischemia in COVID-19 patients.

Purpose of the Study:

  • To review the current literature on cerebrovascular disease (CVD) in the context of COVID-19.
  • To explore the epidemiology and etiology of CVD associated with COVID-19.
  • To highlight the need for further research into the mechanisms underlying cerebral ischemia in COVID-19.

Main Methods:

  • Literature review of case reports and series concerning cerebrovascular disease in COVID-19 patients.
  • Analysis of existing data on the association between COVID-19 and stroke.
  • Synthesis of evidence regarding hypercoagulability and its role in COVID-19-related cerebral ischemia.

Main Results:

  • Reports indicate an increase in stroke cases among young, otherwise healthy adults with COVID-19.
  • The precise mechanisms causing cerebral ischemia in COVID-19 remain under investigation.
  • Evidence points towards hypercoagulability as a significant factor in COVID-19-associated CVD.

Conclusions:

  • COVID-19 may be linked to an increased risk of stroke, particularly in younger populations.
  • The development of cerebrovascular disease in COVID-19 patients is complex and not fully understood.
  • Further investigation is crucial to elucidate the relationship between COVID-19, hypercoagulability, and cerebrovascular events.

Keywords:
COVID-19Cerebrovascular diseaseEndothelitisHipercoagulabilityStrokeYoung

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