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RENISUS Plants and Their Potential Antitumor Effects in Clinical Trials and Registered Patents

Diorge Jônatas Marmitt1, Shanna Bitencourt1, Gustavo Rodrigo da Silva2

  • 1Laboratório de Cultura de Células, Programa de Pós-graduação em Biotecnologia, Universidade do Vale do Taquari (Univates), Lajeado, Brazil.

Nutrition and Cancer
|August 25, 2020
PubMed

Insights

Researchers reviewed studies on medicinal plants and compounds for cancer treatment. Prostate cancer research was most common, with Glycine max, Curcuma longa, and Zingiber officinale showing antitumor potential in clinical trials and patents.

Area of Science:

  • Oncology and Ethnobotany: Investigating natural products for cancer therapy.

Background:

  • Cancer remains a leading cause of death globally, necessitating novel therapeutic strategies.
  • Existing treatments have limitations, fueling the search for new bioactive molecules with antitumor properties.

Purpose of the Study:

  • To systematically review scientific studies, clinical trials, and patents involving National Relation of Medicinal Plants of Interest to the Unified Health System (RENISUS) plants and their derivatives for antitumor potential.

Main Methods:

  • A systematic review of scientific literature, clinical trials, and patent databases was conducted.
  • Focus was placed on RENISUS-registered plants and their derivative compounds exhibiting anticancer activity.

Main Results:

  • Studies covered 19 distinct cancer types, with prostate cancer receiving the most research attention.
  • Key species investigated include Glycine max, Curcuma longa, and Zingiber officinale.
  • Phytochemicals like curcumin and soy isoflavones were frequently evaluated in clinical trials and patents.

Conclusions:

  • Medicinal plants and their compounds show significant promise as sources for novel cancer therapies.
  • Further research and clinical validation are warranted to translate these findings into effective treatments, particularly for prostate cancer.

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