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[Panencephalopathy of the Creutzfeldt-Jakob disease type]
H J Gertz1, G Stoltenburg, F Cruz-Sanchez
1Institut für Neuropathologie, Klinikum Steglitz der Freien Universität Berlin.
Der Nervenarzt
|February 1, 1988
Abstract:
Creutzfeldt-Jakob disease (CJD) occurring in later life has a duration of about one year. Gait disturbance, myoclonic jerks, dementia and akinetic mutism occur. Post-mortem examination of the brain shows nerve cell loss, gliosis and spongiform changes of the grey matter. Clinical and neuropathological features of a case of the panencephalopathic type of CJD, with additional extensive degeneration of the cerebral white matter, are described. The panencephalopathic type of CJD is characterized clinically by a longer duration and a biphasic course.