Related Experiment Video

Updated: Dec 11, 2025

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.1K

National recommendations on pediatric donation

Antonio Rodríguez Núñez1, Alicia Pérez Blanco2,

  • 1Sección de Pediatría Crítica, Cuidados Intermedios y Paliativos Pediátricos, Hospital Clínico Universitario de Santiago de Compostela, Coruña, Spain.

Anales De Pediatria
|August 25, 2020
PubMed

Insights

Spain aims to enhance pediatric organ donation, including donation after circulatory death, by streamlining procedures and addressing ethical considerations for newborns and children. This initiative seeks to improve organ availability and ensure family-centered care during a critical time.

Area of Science:

  • Pediatric transplantation
  • Organ donation ethics
  • Public health policy

Background:

  • Spain is a leader in organ donation and transplantation.
  • There is a need to improve pediatric donation rates, particularly donation after circulatory determination of death.
  • Ethical considerations and procedural complexities impact pediatric donation.

Purpose of the Study:

  • To facilitate organ and tissue donation procedures for newborns and children.
  • To analyze and address ethical dilemmas associated with pediatric donation.
  • To establish ethical standards for pediatric organ and tissue donation.

Main Methods:

  • Summarizes a consensus report from the Organización Nacional de Trasplantes and the Spanish Pediatrics Association.
  • Discusses ethical principles for pediatric donation.
  • Reviews clinical assessment, death determination, and intensive care management of pediatric donors.
  • Examines donation after circulatory determination of death and donation in specific pediatric populations (e.g., newborns with severe malformations, children receiving palliative care).

Main Results:

  • Provides a framework for improving pediatric donation processes.
  • Highlights the ethical imperative of considering organ and tissue donation in all suitable pediatric deaths.
  • Addresses specific challenges in donation from newborns and children in palliative care.

Conclusions:

  • Systematically considering organ and tissue donation in pediatric deaths is an ethical standard.
  • Improving pediatric donation is crucial for meeting transplantation needs.
  • Ensuring family-centered care is paramount in the donation process for children.

Keywords:
Brain deathChildrenDonation after the circulatory determination of deathEthicsFamily-centered careNewbornsOrgan donationPalliative careSurrogate consentTransplantationWithholding and withdrawal of life sustaining measures

More Related Videos

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

7.6K
A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death06:40

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

415

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
209
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
703
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
131
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
148
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
172
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
108