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Acute aortic thrombosis in COVID-19
Ciro Baeza1, Alejandro González1, Patricia Torres1
1Department of Vascular Surgery, University Hospital Fundación Jiménez Díaz, Madrid, Spain.
Insights
This study reports three cases of acute aortic thrombosis in patients with COVID-19. The findings suggest a potential link between SARS-CoV-2 infection and aortic vascular events.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Cardiology
Background:
- Acute aortic occlusion is a rare condition with high mortality.
- The SARS-CoV-2 coronavirus disease (COVID-19) pandemic poses significant global health challenges.
- COVID-19 is associated with a pro-inflammatory state and coagulopathy, potentially involving macrophage activation.
Observation:
- Three cases of acute infrarenal abdominal aortic thrombosis were observed in COVID-19 patients within a two-week period.
- These patients were treated at our hospital during the COVID-19 pandemic.
- The presentation of aortic thrombosis in these patients was acute.
Findings:
- The study presents a series of three cases linking COVID-19 infection to acute aortic thrombosis.
- The findings suggest a potential association between SARS-CoV-2 infection and the development of aortic thrombosis.
- Inflammatory processes and coagulopathy in COVID-19 may contribute to aortic thrombosis.
Implications:
- This case series highlights a potential, previously underreported complication of COVID-19.
- Awareness of aortic thrombosis as a possible manifestation of COVID-19 is crucial for clinicians.
- Further research is needed to elucidate the mechanisms linking COVID-19 to aortic thrombosis and to inform clinical management.
Abstract:
Acute aortic occlusion is an infrequent disease but with significant mortality. The new pandemic of the SARS-CoV-2 coronavirus disease (COVID-19) represents a great challenge for health systems. This contagious disease is generating high infection and mortality rates in several countries. It is speculated that the inflammatory process accompanying the infection is triggered by massive macrophage activation and is associated with the development of coagulopathy. We present three cases of COVID-19 patients, treated in our hospital during a period of 2 weeks, who presented with an acute thrombosis of the infrarenal abdominal aorta.
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