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Published on: June 18, 2021
Clinical Features of COVID-19 in a Young Man with Massive Cerebral Hemorrhage-Case Report
Yi Bao1, Shu Yu Lin2, Zhao Hui Cheng1
1Department of Neurology, Taihe Hospital Affiliated to Hubei University of Medicine, Shiyan City, Hubei Province China.
Insights
This case study highlights a COVID-19 patient whose initial symptom was cerebral hemorrhage. Plasma transfusion from recovered individuals proved effective for this critically ill patient.
Area of Science:
- Neurology
- Infectious Diseases
- Critical Care Medicine
Background:
- Coronavirus disease 2019 (COVID-19) is a global pandemic with significant morbidity and mortality.
- Cerebrovascular events have not been widely reported as a primary manifestation of COVID-19.
- This case presents a unique initial symptom of COVID-19.
Purpose of the Study:
- To report the clinical features of a COVID-19 patient presenting with cerebral hemorrhage.
- To investigate the potential link between COVID-19 and cerebrovascular complications.
- To evaluate the efficacy of convalescent plasma therapy in severe COVID-19 cases.
Main Methods:
- Case report of a COVID-19 patient with cerebral hemorrhage.
- Clinical observation including post-craniotomy fever and intracranial infection.
- Cerebrospinal fluid testing and treatment with anti-infection therapy and convalescent plasma.
Main Results:
- The patient's initial symptom was cerebral hemorrhage, a rare presentation of COVID-19.
- Intracranial infection was diagnosed post-craniotomy, indicated by persistent high fever.
- Treatment with anti-infection measures and convalescent plasma led to gradual symptom improvement.
Conclusions:
- COVID-19 may be associated with cerebrovascular complications such as cerebral hemorrhage.
- Convalescent plasma transfusion is a potentially effective treatment for critically ill COVID-19 patients.
- Early diagnosis and comprehensive management are crucial for patients with severe COVID-19 and neurological complications.
Abstract:
COVID-19 is currently a pandemic in the world, can invade multiple systems, and has a high morbidity and mortality. So far, no cases of acute cerebrovascular disease have been reported. This article reports the clinical features of a COVID-19 patient whose first symptom was cerebral hemorrhage. More importantly, after the craniotomy, the patient had high fever and it was difficult to retreat. After cerebrospinal fluid testing, it was determined that an intracranial infection had occurred. After anti-infection and plasma infusion of the recovered person, the patient's symptoms gradually improved. This case suggests that COVID-19 may infringe on cerebral blood vessels and cause cerebral hemorrhage. Transfusion of plasma from rehabilitation patients is effective for critically ill patients.
