Related Experiment Video
Updated: Dec 11, 2025
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Coronavirus Disease 2019 (COVID-19) as a Multi-Systemic Disease and its Impact in Low- and Middle-Income Countries
Mazou Ngou Temgoua1, Francky Teddy Endomba2, Jan René Nkeck1
1Department of Internal Medicine and Specialities, Faculty of Medicine and Biomedical Sciences, University of Yaounde, Yaoundé, Cameroon.
Insights
Coronavirus disease 2019 (COVID-19) impacts multiple organs due to viral effects and inflammation. Integrating this multi-systemic understanding into patient management can improve outcomes, especially in developing nations.
Area of Science:
- Infectious Diseases
- Public Health
- Pathology
Background:
- Coronavirus disease 2019 (COVID-19) rapidly became a global pandemic, declared by the World Health Organization (WHO).
- Extensive research has focused on understanding COVID-19's pathogenesis and clinical manifestations.
- The disease's impact extends beyond the respiratory system, affecting nearly all organs.
Purpose of the Study:
- To emphasize the multi-systemic nature of COVID-19.
- To advocate for integrating this comprehensive understanding into clinical management strategies.
- To highlight the potential benefits for patient outcomes, particularly in resource-limited settings.
Main Methods:
- Review of existing literature on COVID-19 pathogenesis and clinical presentation.
- Analysis of the direct viral effects and the induced inflammatory response.
- Consideration of the disease's impact across various organ systems.
Main Results:
- COVID-19 demonstrates a multi-systemic impact, affecting numerous organs.
- Both direct viral action and widespread inflammation contribute to the disease's pathology.
- The multi-systemic nature necessitates a holistic approach to patient care.
Conclusions:
- Healthcare providers must recognize and manage the multi-systemic effects of COVID-19.
- Adopting a comprehensive management strategy can lead to improved patient outcomes.
- This approach is crucial for mitigating the disease's burden, especially in low- and middle-income countries (LMICs).
Abstract:
Currently, the coronavirus disease 2019 (COVID-19) is the priority of the global health agenda. Since the first case was reported in Wuhan, China, this infection has continued to spread and has been considered as a pandemic by the World Health Organization (WHO) within 3 months of its outbreak. Several studies have been done to better understand the pathogenesis and clinical aspects of the disease. It appears that COVID-19 affects almost all body organs due to the direct effect of the virus and its induced widespread inflammatory response. This multi-systemic aspect of the disease has to be inculcated in COVID-19 management by health providers to improve patient outcomes. This strategy could help curb the burden of the disease especially in low- and middle-income countries (LMICs) like most African countries where the pandemic is at an "embryonic" stage.
More Related Videos
Related Concept Videos
01:18Factors Affecting Illness
For instance, risk factors are connected to illness,...
01:26Methods Of Healthcare Delivery System
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
01:26Principles of Disease Surveillance
01:20COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
01:30Coronary Artery Disease III: Clinical Manifestations
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation