Jove
Visualize
Contact Us

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Magnetic field sensors using VO<sub>2</sub>/Fe<sub>3</sub>O<sub>4</sub>nanoparticle devices<sup></sup>.

Nanotechnology·2023
Same author

Bio-mimetic synthetic cell hydrogel magnetometer.

Bioinspiration & biomimetics·2018
Same author

Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response.

Micromachines·2018
Same author

Piezoresistive pressure sensors in the measurement of intervertebral disc hydrostatic pressure.

The spine journal : official journal of the North American Spine Society·2009
Same author

Multiscale mechanics of hierarchical structure/property relationships in calcified tissues and tissue/material interfaces.

Materials science & engineering. A, Structural materials : properties, microstructure and processing·2008
Same author

Near-field microwave microscope and electron-spin-resonance detection: ruby crystal surface.

Applied optics·2006
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 11, 2025

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K

Whole virus detection using aptamers and paper-based sensor potentiometry.

Subhashish Dolai1, Massood Tabib-Azar1

  • 1University of Utah 201 Presidents' Cir Salt Lake City UT USA.

Medical Devices & Sensors
|August 25, 2020
PubMed
Summary

A novel paper-based sensor detects the whole Zika virus using aptamers and a potentiometric measurement. This inexpensive, flexible sensor shows potential for portable diagnostics, similar to a P-N junction.

More Related Videos

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
12:23

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Published on: September 7, 2022

1.9K
Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment
08:34

Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment

Published on: March 2, 2016

9.9K

Related Experiment Videos

Last Updated: Dec 11, 2025

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
08:22

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

12.5K
In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
12:23

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Published on: September 7, 2022

1.9K
Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment
08:34

Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment

Published on: March 2, 2016

9.9K

Area of Science:

  • Biosensors
  • Nanotechnology
  • Materials Science

Background:

  • Paper-based sensors offer flexibility, recyclability, and low cost.
  • Microfluidic platforms are increasingly integrated with electronics for diagnostics.

Purpose of the Study:

  • To develop a paper-based potentiometric sensor for detecting the whole Zika virus.
  • To characterize the sensor's sensitivity and minimum detectable signal.

Main Methods:

  • A paper sensor was fabricated with silver paint contacts and dipped in a buffer with aptamers.
  • Zika virus was added, immobilizing and binding to aptamers, creating a concentration gradient.
  • Atomic force microscopy and Raman spectroscopy confirmed immobilization; potentiometric measurements were taken.

Main Results:

  • The sensor detected the whole Zika virus with a minimum sensitivity of 0.26 nV/Zika.
  • A minimum detectable signal (MDS) of 2.4x10^7 Zika was achieved.
  • Potential measurements became reproducibly more negative upon Zika addition.

Conclusions:

  • The paper-based potentiometric sensor effectively detects Zika virus.
  • The sensor functions similarly to a P-N junction, leveraging electrochemical potentials.
  • Integration with a liquid crystalline display (LCD) enables portable readout.