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Published on: October 23, 2020
The association of race and COVID-19 mortality
Ladan Golestaneh1, Joel Neugarten1, Molly Fisher1
1Department of Medicine, Renal Division, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, United States.
Insights
Black individuals experienced significantly higher COVID-19 mortality compared to White individuals. This increased risk was not fully explained by factors like age, comorbidities, or sociodemographic disparities.
Area of Science:
- Epidemiology
- Public Health
- Health Disparities
Background:
- COVID-19 has disproportionately impacted the Black population in the United States.
- Understanding the specific risks and contributing factors for this disparity is crucial for public health interventions.
Purpose of the Study:
- To investigate the association between race and COVID-19 related hospitalization and mortality.
- To compare the relative risk of hospitalization and death in Black and Hispanic populations versus the White population during pre-COVID and COVID periods.
Main Methods:
- A cohort study of 505,992 patients from Bronx Montefiore Health System (BMHS) was conducted.
- Data from pre-COVID (1/1/20-2/15/20) and COVID (3/1/20-4/15/20) periods were analyzed.
- Logistic modeling was used to compare hospitalization and mortality rates, adjusting for clinical and sociodemographic factors.
Main Results:
- Black patients showed a 1.6 times higher adjusted odds of death during the COVID period compared to White patients (p=0.001).
- A significant increase in Black mortality risk was observed from the pre-COVID to the COVID period (p for interaction=0.02).
- While adjustments for clinical and social factors reduced the disparity, they did not fully explain the increased Black mortality.
Conclusions:
- The study confirms a higher COVID-19 mortality rate among Black individuals within the BMHS system.
- This disparity is incompletely explained by age, comorbidities, and available sociodemographic data.
- Further research is needed to fully elucidate the complex factors contributing to this health inequity.
Background:
COVID-19 mortality disproportionately affects the Black population in the United States (US). To explore this association a cohort study was undertaken.
Methods:
We assembled a cohort of 505,992 patients receiving ambulatory care at Bronx Montefiore Health System (BMHS) between 1/1/18 and 1/1/20 to evaluate the relative risk of hospitalization and death in two time-periods, the pre-COVID time-period (1/1/20-2/15/20) and COVID time-period (3/1/20-4/15/20). COVID testing, hospitalization and mortality were determined with the Black and Hispanic patient population compared separately to the White population using logistic modeling. Evaluation of the interaction of pre-COVID and COVID time periods and race, with respect to mortality was completed.
Findings:
A total of 9,286/505,992 (1.8%) patients were hospitalized during either or both pre-COVID or COVID periods. Compared to Whites the relative risk of hospitalization of Black patients did not increase in the COVID period (p for interaction=0.12). In the pre- COVID period, compared to Whites, the odds of death for Blacks and Hispanics adjusted for comorbidity was statistically equivalent. In the COVID period compared to Whites the adjusted odds of death for Blacks was 1.6 (95% CI 1.2-2.0, p = 0.001). There was a significant increase in Black mortality risk from pre-COVID to COVID periods (p for interaction=0.02). Adjustment for relevant clinical and social indices attenuated but did not fully explain the observed difference in Black mortality.
Interpretation:
The BMHS COVID experience demonstrates that Blacks do have a higher mortality with COVID incompletely explained by age, multiple reported comorbidities and available metrics of sociodemographic disparity.
Funding:
N/A.
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